[HTML][HTML] l-DOPA and consolidation of fear extinction learning among women with posttraumatic stress disorder
This study tested whether l-DOPA delivered during the consolidation window following fear
extinction learning reduces subsequent fear responding among women with PTSD. Adult
women diagnosed with PTSD completed a contextual fear acquisition and extinction task
during fMRI and then immediately received either placebo (n= 34), 100/25 mg l-
DOPA/carbidopa (n= 28), or 200/50 mg l-DOPA/carbidopa (n= 29). Participants completed a
resting-state scan before the task and again 45 min following drug ingestion to characterize …
extinction learning reduces subsequent fear responding among women with PTSD. Adult
women diagnosed with PTSD completed a contextual fear acquisition and extinction task
during fMRI and then immediately received either placebo (n= 34), 100/25 mg l-
DOPA/carbidopa (n= 28), or 200/50 mg l-DOPA/carbidopa (n= 29). Participants completed a
resting-state scan before the task and again 45 min following drug ingestion to characterize …
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