[PDF][PDF] L-Proline: An Efficient and Selective Catalyst for Transamidation of Thioamides with Amines

SN Rao, DC Mohan, S Adimurthy - J Biomol Res Ther, 2016 - researchgate.net
J Biomol Res Ther, 2016researchgate.net
… In continuation of our interest on the development of environmentfriendly transamidation
catalysts [35-39], we wish to report a general L-proline-catalysed transthioamidation of
primary amides with amines under solvent-free conditions [40]. To the best of our
knowledge very rare reports available for the … In summary, we have reported the synthesis
of variety of thioamides using easily available L-proline catalysed transamidation of various
thioamides with amines under neat conditions. With this method a variety of corresponding …
Abstract
L-Proline catalysed transthioamidation of primary thioamides with amines under solvent-free conditions has been described. The transthioamidation is compatible with wide range of amines with yields up to 97%.
researchgate.net
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