[HTML][HTML] Lactobacillus-deficient cervicovaginal bacterial communities are associated with increased HIV acquisition in young South African women
Elevated inflammation in the female genital tract is associated with increased HIV risk.
Cervicovaginal bacteria modulate genital inflammation; however, their role in HIV
susceptibility has not been elucidated. In a prospective cohort of young, healthy South
African women, we found that individuals with diverse genital bacterial communities
dominated by anaerobes other than Gardnerella were at over 4-fold higher risk of acquiring
HIV and had increased numbers of activated mucosal CD4+ T cells compared to those with …
Cervicovaginal bacteria modulate genital inflammation; however, their role in HIV
susceptibility has not been elucidated. In a prospective cohort of young, healthy South
African women, we found that individuals with diverse genital bacterial communities
dominated by anaerobes other than Gardnerella were at over 4-fold higher risk of acquiring
HIV and had increased numbers of activated mucosal CD4+ T cells compared to those with …
[PDF][PDF] Lactobacillus-Deficient Cervicovaginal Bacterial Communities Are Associated with Increased HIV Acquisition in Young South African Women
N Padavattan, C Desai, L Droit, A Moodley, M Dong… - Immunity, 2017 - academia.edu
Elevated inflammation in the female genital tract is associated with increased HIV risk.
Cervicovaginal bacteria modulate genital inflammation; however, their role in HIV
susceptibility has not been elucidated. In a prospective cohort of young, healthy South
African women, we found that individuals with diverse genital bacterial communities
dominated by anaerobes other than Gardnerella were at over 4-fold higher risk of acquiring
HIV and had increased numbers of activated mucosal CD4+ T cells compared to those with …
Cervicovaginal bacteria modulate genital inflammation; however, their role in HIV
susceptibility has not been elucidated. In a prospective cohort of young, healthy South
African women, we found that individuals with diverse genital bacterial communities
dominated by anaerobes other than Gardnerella were at over 4-fold higher risk of acquiring
HIV and had increased numbers of activated mucosal CD4+ T cells compared to those with …
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