Large-scale chemical screen identifies Gallic acid as a geroprotector for human stem cells

H Shan, L Geng, X Jiang, M Song, J Wang, Z Liu… - Protein & …, 2022 - academic.oup.com
The interventions that slow aging or promote healthy aging may provide preventative
measures for age-related diseases (Zhang et al., 2015). Therefore, it is crucial to identify
drugs that target aging-related pathologies and improve healthspan in geroscience
research. Using model organisms such as C. elegans and rodents, several small molecules
capable of alleviating the onset or progression of aging, including rapamycin, nicotinamide
mononucleotide, and metformin, have been discovered (Partridge et al., 2020). However …

[PDF][PDF] Large-scale chemical screen identifies Gallic acid as a geroprotector for human stem cells

S Hezhen, G Lingling, J Xiaoyu, S Moshi, W Jianxun… - 2021 - ir.ioz.ac.cn
The interventions that slow aging or promote healthy aging may provide preventative
measures for age-related diseases (Zhang et al., 2015). Therefore, it is crucial to identify
drugs that target aging-related pathologies and improve healthspan in geroscience
research. Using model organisms such as C. elegans and rodents, several small molecules
capable of alleviating the onset or progression of aging, including rapamycin, nicotinamide
mononucleotide, and metformin, have been discovered (Partridge et al., 2020). However …
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