Limited bedding and nesting increases ethanol drinking in female rats

BJ Parks, P Salazar, L Morrison, MK McGraw… - Pharmacology …, 2024 - Elsevier
Prenatal opioid exposure (POE) and postnatal adverse experiences are early life adversities
(ELA) that often co-occur and increase problematic alcohol (EtOH) drinking during
adolescence. We investigated the relationship between POE, postnatal adversity, and
adolescent EtOH drinking in rats. We also sought to determine whether ELAs affect alpha-
adrenoceptor density in the brain because the noradrenergic system is involved in
problematic alcohol drinking and its treatment. We hypothesized that the combination of …
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