Lipid profile in mild subclinical hypothyroidism: systematic review and meta-analysis.

Y Treister-Goltzman, S Yarza, R Peleg - Minerva endocrinology, 2021 - europepmc.org
Minerva endocrinology, 2021europepmc.org
… The results of published papers on mild subclinical hypothyroidism (MSCH) with TSH
below10 mIU/L are contradictory. The objective of the study was to conduct a systematic
review and meta-analysis on lipid profiles in a population of patients with MSCH (TSH10>
mIU/L and normal T3, T4) in comparison with euthyroid subjects. … A systematic review of
the studies and a meta-analysis using R software (version 3.6.1) were performed. Thirty-five
case control and cohort studies were included in the …
Conclusions
MSCH is associated with an increase in major atherogenic lipoproteins and should be viewed as a cardiovascular risk factor.
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