Previously, we have proposed mupirocin‐in‐liposomes‐in‐hydrogel delivery system as
advanced delivery system with the potential in treatment of burns. In the current studies, we
evaluated the system for its cytotoxicity, ability to prevent biofilm formation, act on the mature
biofilms, and finally determined its potential as wound treatment in in vivo mice burn model.
The system was found to be nontoxic against HaCaT cells, that is, keratinocytes. It was safe
for use and exhibited antibiofilm activity against S. aureus biofilms, although the activity was …