Purpose Evidence exists to support the peripheral analgesic effect of local administration of
ketamine (LAK) after third molar surgery. The aim of the present systematic review and meta-
analysis was to determine the efficacy of LAK in the control of pain, swelling, and trismus
after third molar surgery. Materials and Methods The study design was a systematic review
with a meta-analysis of the effect of LAK after third molar surgery. A search in electronic
databases was performed from September 2017 to February 2019. Only prospective clinical …