Importance Benzodiazepines are considered first-line therapy for pediatric status
epilepticus. Some studies suggest that lorazepam may be more effective or safer than
diazepam, but lorazepam is not Food and Drug Administration approved for this indication.
Objective To test the hypothesis that lorazepam has better efficacy and safety than diazepam
for treating pediatric status epilepticus. Design, Setting, and Participants This double-blind,
randomized clinical trial was conducted from March 1, 2008, to March 14, 2012. Patients …