Low serum levels of cathelicidin LL-37 in leprosy
M Matzner, AR Al Samie, HM Winkler, J Nemeth… - Acta tropica, 2011 - Elsevier
The antimicrobial peptide cathelicidin LL-37 possesses antituberculous activity, its
association with other mycobacterial diseases, such as leprosy, is unknown. We studied
serum cathelicidin and 25OH-vitamin D3 levels in 29 leprosy patients and 19 healthy
individuals from Yemen. Cathelicidin levels were significantly lower in both treated (n= 15)
and untreated leprosy patients (n= 14) when compared to controls (P< 0.001). Within leprosy
patients, levels were lower in those who very recently developed disease (untreated group) …
association with other mycobacterial diseases, such as leprosy, is unknown. We studied
serum cathelicidin and 25OH-vitamin D3 levels in 29 leprosy patients and 19 healthy
individuals from Yemen. Cathelicidin levels were significantly lower in both treated (n= 15)
and untreated leprosy patients (n= 14) when compared to controls (P< 0.001). Within leprosy
patients, levels were lower in those who very recently developed disease (untreated group) …
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