Macrophage antioxidant enzymes regulate Chlamydia pneumoniae chronicity: Evidence of the effect of redox balance on host–pathogen relationship
AA Azenabor, K Muili, JF Akoachere, A Chaudhry - Immunobiology, 2006 - Elsevier
Latency, chronicity and recurrent nature are the features of Chlamydia pneumoniae biology
which play a central role in the course and outcome of C. pneumoniae–host interaction.
Since redox status is directly an indicator of inflammatory response via molecular signaling
mechanisms, we decided to study the regulatory role of macrophage cellular redox balance
on the molecular indices of C. pneumoniae chronicity. We examined GSH–GSSG status, the
activities of antioxidant enzymes (SOD, GPx and γ-GCS), along with their protein and gene …
which play a central role in the course and outcome of C. pneumoniae–host interaction.
Since redox status is directly an indicator of inflammatory response via molecular signaling
mechanisms, we decided to study the regulatory role of macrophage cellular redox balance
on the molecular indices of C. pneumoniae chronicity. We examined GSH–GSSG status, the
activities of antioxidant enzymes (SOD, GPx and γ-GCS), along with their protein and gene …
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