… mouse interleukin 10 (IL-10) was exceedingly potent at suppressing the ability of mouse
peritoneal macrophages (mOb) to release tumor necrosis factor a (TNF-o~). The ICs0 of IL-10 …

… IL-4, and IL-10 are the only presently … macrophage-deactivating effects. However, none of
them can be categorized as purely macrophage deactivating since they also exert macrophage…

… The release of inflammatory molecules is regulated and counterbalanced by the coordinated
expression of anti-inflammatory cytokines such as interleukin 10 (IL-10) (34). IL-10 is an …

… Because interleukin-10 (IL-10) modulates macrophage activation in vitro and its expression
… IL-10 influenced the macrophage phenotype in mdx muscle and whether changes in IL-10 …

… We conclude that IL-10 and TGF-beta induce different phenotypes of macrophage deactivation,
and deactivate macrophages by different mechanisms: IL-10 promotes degradation of …

… tween the macrophage inhibitory effect of PGE2 and IL-10. Evidence is presented to support
an important role for IL-10 in the deactivation of murine peritoneal macrophages by PGE2. …

… lL-10 on intracellular killing activity by macrophage. We first examined the bacterial burden
in macrophage, since IL-10, macrophage deactivating … killing activity of macrophages. When …

… monocytes/macrophages and T cell subsets including Tr1, Treg, and Th1 cells. IL-10 acts …
In monocytes/macrophages, IL-10 diminishes the production of inflammatory mediators and …

… highlight IL-10 as a critical homeostatic macrophage-conditioning agent in the colon and
define intestinal CX 3 CR1 hi macrophages as a … Macrophage deactivation by interleukin 10. …

… , is not sufficient: aC-terminal ∼15 amino acid segment of IL-10R1, along with stat3,
plays a keyfunctional role in inhibition of macrophage activation by IL-10, but not inother IL-10 …