Macrophage physiology in the eye

HR Chinnery, PG McMenamin, SJ Dando - … Journal of Physiology, 2017 - Springer
… , phenotype, and physiological role of ocular macrophages, and provide a … macrophages
located within various ocular tissues and highlight their role in normal physiology of the eye

An eye on Kupffer cells: development, phenotype and the macrophage niche

A Elchaninov, P Vishnyakova, E Menyailo… - International Journal of …, 2022 - mdpi.com
… According to the Ms4a3 gene expression dynamics, the rates and extent of the resident
macrophage replacement with monocytic macrophages depends on the type (model) of …

Dendritic cell physiology and function in the eye

JV Forrester, H Xu, L Kuffová, AD Dick… - Immunological …, 2010 - Wiley Online Library
macrophage and dendritic cell (DC) populations in the eye … no DCs, occasional macrophages
(perivascularly distributed), … The privileged status of the eye, however, is relative, as it is …

Ocular macrophage origin and heterogeneity during steady state and experimental choroidal neovascularization

S Droho, BR Thomson, HM Makinde, CM Cuda… - Journal of …, 2020 - Springer
… To better understand ocular macrophages at steady state, we dissected eyes into iris,
retina, and choroid fractions to determine the contribution from each tissue to each …

The eye: a window to the soul of the immune system

VL Perez, AM Saeed, Y Tan, M Urbieta… - Journal of …, 2013 - Elsevier
… responses in the eye, with T cells playing a central role in combination with neutrophils and
macrophages. In addition, we emphasize the advantage of using the eye as a model for in …

IL10-driven STAT3 signalling in senescent macrophages promotes pathological eye angiogenesis

R Nakamura, A Sene, A Santeford, A Gdoura… - Nature …, 2015 - nature.com
… and STAT3 activation in macrophages reverses the ageing … macrophages into eyes of
old mice significantly reduces the amount of CNV. Systemic and CD163 + eye macrophages

The role of retinal pigment epithelial cells in regulation of macrophages/microglial cells in retinal immunobiology

AW Taylor, S Hsu, TF Ng - Frontiers in Immunology, 2021 - frontiersin.org
… to be therapeutically adapted to suppress inflammation within the eye and in other tissues. …
eye. The antigen is picked up and processed for presentation by F4/80 positive macrophages

THE ROLE OF MACROPHAGES IN THE DEVELOPMENT OF HUMAN EYE STRUCTURES IN PRENATAL ONTOGENESIS

ES Mozhilevskaya, YV Sadovaya… - European Journal of …, 2021 - elibrary.ru
… interaction of macrophages and cells of the forming eye vesicle. Macrophage elements play
… death during the development of the human eye, participate in the regulation of proliferative …

New insights into mononuclear phagocyte biology from the visual system

NJ Reyes, EG O'Koren, DR Saban - Nature Reviews Immunology, 2017 - nature.com
… parts of the eye include: dendritic cells (DCs) and macrophages 29 in the cornea; DCs
and macrophages 30 in the iris; macrophages 30 in the ciliary body; macrophages 30 in the …

Eye: Anatomy, physiology and barriers to drug delivery

K Cholkar, SR Dasari, D Pal, AK Mitra - Ocular transporters and receptors, 2013 - Elsevier
… Critical anatomical and physiological factors that regulate drug absorption are discussed. Of
… periocular and intravitreal for back of the eye tissues are mostly preferred and recommended…