Magnetically directed two-dimensional crystallization of OmpF membrane proteins in block copolymers
Two-dimensional (2D) alignment and crystallization of membrane proteins (MPs) is
increasingly important in characterizing their three-dimensional (3D) structure, in designing
pharmacological agents, and in leveraging MPs for biomimetic devices. Large, highly
ordered MP 2D crystals in block copolymer (BCP) matrices are challenging to fabricate, but
a facile and scalable technique for aligning and crystallizing MPs in thin-film geometries
would rapidly translate into applications. This work introduces a novel method to grow larger …
increasingly important in characterizing their three-dimensional (3D) structure, in designing
pharmacological agents, and in leveraging MPs for biomimetic devices. Large, highly
ordered MP 2D crystals in block copolymer (BCP) matrices are challenging to fabricate, but
a facile and scalable technique for aligning and crystallizing MPs in thin-film geometries
would rapidly translate into applications. This work introduces a novel method to grow larger …
[引用][C] Magnetically Directed Two-Dimensional Crystallization of OmpF Membrane Proteins in Block Copolymers
B Mahnoush, C Po-Lin, DZ Rita, D Kaushik, W Thomas… - 2016
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