We investigate whether adherence to dominant masculine norms and choice of college major are related among undergraduate men in the United States. Our results indicate that men’s level of conformity to certain masculine norms is associated with their postsecondary field of study. In particular, we find men’s adherence to the masculine norm of emotional control is associated negatively with selecting majors from such academic fields as clinical and health sciences or arts and humanities compared to science, technology, engineering, and mathematics (STEM) and doctoral-track medicine (e.g., pre-medicine and pre-dentistry). Conformity to the masculine norm to focus on work is related negatively to choosing a major in arts and humanities or communication and media fields compared to STEM and doctoral-track medicine fields. These results suggest ways that dominant social norms about masculinity may contribute to gender segregation of postsecondary fields of study.