… of the binding sites of Matrin3 are located in intronic regions of … Matrin3 preferentially
recognized pyrimidine-rich sequences as binding motifs, which we confirmed by an in vitro binding …

… by PTBP1 were also bound by Matrin3, Matrin3 could control alternative splicing in a PTBP1-…
suggest that Matrin3 is a splicing regulator that targets intronic pyrimidine-rich sequences. …

… that Matrin3 plays a role in controlling alternative splicing … Most of the remaining motifs had
high pyrimidine content, with … iCLIP shows that Matrin3 binds directly to the introns flanking …

… nuclear export, modulating alternative splicing, and managing … binding to the intronic regions
of RNAs with pyrimidine-rich … Protein-RNA interaction analysis revealed Matrin3 directly …

… , but exons adjacent to introns with MATR3 binding sites were disproportionately … directly
or indirectly contributes to RNA splicing. For example, MATR3 and polypyrimidine tract binding …

… unclear whether MATR3 directly or indirectly contributes to RNA splicing. For example, …
Matrin3 binds directly to intronic pyrimidine-rich sequences and controls alternative splicing. …

… in the DNA/RNA-binding protein Matrin-3 (MATR3) are linked … -UTR, 5′-UTR, intron and
exons were obtained from eCLIP … regulator complexes to regulate alternative splicing [38, 39]. …

… exon-intron structure based on annotated Reference Sequence (… frequent category of
alternative splicing which includes both … transcripts in KO which were directly bound by MATR3 …

… intron of the C9orf72 gene. The accumulation of repetitive … be binding to G4C2 repeats directly
and associate with other … alterations of alternative splicing and alternative polyadenylation …

… (2017) Matrin3 binds directly to intronic pyrimidine-rich sequences and controls alternative
splicing. Genes Cells 22, 785–798 https://doi.org/10.1111/gtc.12512 40 Maris, C., Dominguez…