Recently, wireless sensor networks (WSNs) attracted the attention of searchers, due to the critical role in several applications like environmental monitoring, habitat study, military surveillance, smart homes, and patient observation. Because nodes energy sources are limited, the consumption of energy is the major problem in WSN that directly affects the performance of WSN. Now there is a necessity for a different protocol considering energy consumption, for this a mixture between chain transmission and grid clustering chosen. In this article, we present the “Power Efficient Grid-Chain Routing Protocol in WSN” protocol to extend the vitality of the network. In the first phase, the grid algorithm applied to divide the nodes into virtual cells. Then the data transmissions used chain transmission in intra-cluster and in inter-cluster, where each node communicates with their neighbor. Our proposed submitted protocol simulated in MATLAB. The simulations demonstrated that our protocol maximizes the stability of the network and reduced the energy consumption best than protocol LEACH.