[HTML][HTML] Melanoma patient-derived xenografts accurately model the disease and develop fast enough to guide treatment decisions
The development of novel therapies against melanoma would benefit from individualized
tumor models to ensure the rapid and accurate identification of biomarkers of therapy
response. Previous studies have suggested that patient-derived xenografts (PDXes) could
be useful. However, the utility of PDXes in guiding real-time treatment decisions has only
been reported in anecdotal forms. Here tumor biopsies from patients with stage III and IV
metastatic malignant melanoma were transplanted into immunocompromised mice to …
tumor models to ensure the rapid and accurate identification of biomarkers of therapy
response. Previous studies have suggested that patient-derived xenografts (PDXes) could
be useful. However, the utility of PDXes in guiding real-time treatment decisions has only
been reported in anecdotal forms. Here tumor biopsies from patients with stage III and IV
metastatic malignant melanoma were transplanted into immunocompromised mice to …
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