Melatonin, originally … Melatonin regulates the sleep/wake cycle, other circadian and seasonal
rhythms, and acts as an immunostimulator and cytoprotective agent. Circulating melatonin …

… experimental methods which inhibit melatonin synthesis and secretion induce a state of
immunodepression which is counteracted by melatonin. In general, melatonin seems to have an …

… melatonin dose mean that the current PRCs for melatonin are not ideal. A single pulse PRC
for melatonin … of phase shift and optimum time of melatonin administration. The study of free-…

Publisher Summary Molecular biology has dispersed some of the myths surrounding melatonin.
Melatonin production sites can be clearly identified by detecting message and protein …

Three centuries ago, the French philosopher René Descartes described the pineal gland as
“the seat of the soul,” but it was not until the late 1950s that melatonin, the principal …

… the role of melatonin in human physiology and disease has emerged, but many functions
and effects of melatonin remain unresolved. This review will focus on data about melatonin in …

… however, has revealed that melatonin is functionally much more … Also, the conflating of
melatonin exclusively with the pineal … melatonin's multiple actions and the evidence that melatonin …

Melatonin is synthesized and secreted during the dark period of the light-dark cycle. Thus,
melatonin … Rhythmic nocturnal melatonin secretion is directly generated by the circadian clock, …

… The pineal hormone melatonin is involved in photic regulations … The melatonin effects are
mediated by the specific high-… Two different G proteins coupled to the melatonin receptors have …

… The circadian rhythm of melatonin production and release, … Melatonin acts through high-affinity
receptors located … applications, exogenous melatonin or a melatonin agonist and …