Membrane Potential Fluctuations Resulting From Submembrane Ca2+ Releases in Rabbit Sinoatrial Nodal Cells Impart an Exponential Phase to the Late Diastolic …

KY Bogdanov, VA Maltsev, TM Vinogradova… - Circulation …, 2006 - Am Heart Assoc
Stochastic but roughly periodic LCRs (L ocal subsarcolemmal ryanodine receptor–mediated
C a2+ R eleases) during the late phase of diastolic depolarization (DD) in rabbit sinoatrial
nodal pacemaker cells (SANCs) generate an inward current (I NCX) via the Na+/Ca2+
exchanger. Although LCR characteristics have been correlated with spontaneous beating,
the specific link between LCR characteristics and SANC spontaneous beating rate, ie,
impact of LCRs on the fine structure of the DD, have not been explicitly defined. Here we …

[引用][C] Membrane potential fluctuations resulting from submembrane Ca^< 2+> releases in rabbit sinoatrial nodal cells impart an exponential phase to the late diastolic …

B KY - Circ Res, 2006 - cir.nii.ac.jp
Membrane potential fluctuations resulting from submembrane Ca^<2+> releases in rabbit
sinoatrial nodal cells impart an exponential phase to the late diastolic depolarization that
controls their chronotropic state | CiNii Research … Membrane potential fluctuations
resulting from submembrane Ca^<2+> releases in rabbit sinoatrial nodal cells impart an
exponential phase to the late diastolic depolarization that controls their chronotropic state …
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