A 42-yr-old man with ulcerative colitis was admitted for investigation of prolonged fever
associated with cholestatic liver tests. Endoscopic retrograde cholangiopancreatography …

… A clinical diagnosis of mesalamine-induced fever and granulomatous hepatitis was made
and the medication was discontinued. Three days later his fever resolved and his liver panel …

… audit revealed 3.2 cases of mesalamine-induced-liver-injury … , cholestatic hepatitis, and
granulomatous hepatitis, mostly in … an isolated mesalamine-induced autoimmune hepatitis in a …

… granulomatous hepatitis: Sulfasalazine has also been reported to cause acute granulomatous
hepatitis … Data with regard to prognosis of mesalamine-induced liver injury is lacking. …

… He was diagnosed with granulomatous hepatitis based on a liver biopsy. The hepatic …
due to granulomatous hepatitis. We report a rare case with granulomatous hepatitis diagnosed …

… granulomatous hepatitis. The patient recovered completely after cessation of mesalazine,
so that a drug-induced granulomatous hepatitis after … agent for the granulomatous hepatitis. …

Background Mesalamine is a first-line drug in the treatment of inflammatory bowel diseases,
while its intolerance occasionally occurs in clinical practice. Most of adverse reactions are …

… Mesalamine-induced lung disease is usually insidious and characterized by progressive
symptoms; pulmonary function tests (PFTs) usually show a restrictive pattern, though a …

… Besides an interesting claim that mesalamines can cause granulomatous hepatitides,[4]
we found five reports by matching the terms “mesalazines” with cholestasis in the Medline. Of …

Discussion Although mesalamine induced hepatotoxicity has a low incidence, it should be
suspected in a patient receiving this drug with sudden liver profile alteration. Since the patient …