Mesenchymal stem cells cultured on a collagen scaffold: In vitro osteogenic differentiation
E Donzelli, A Salvadè, P Mimo, M Viganò… - Archives of oral …, 2007 - Elsevier
OBJECTIVE: Management of periodontal defects has always been a challenge in clinical
periodontics. Recently mesenchymal stem cells (MSC) have been proposed for tissue
regeneration in periodontal disease and repair of large bone defects. Bone regeneration
has to be supported by a scaffold which has to be biocompatible, biodegradable, and able to
support cell growth and differentiation. The aim of this study was to evaluate osteogenic
differentiation of MSC seeded on a collagen scaffold. DESIGN: MSC were obtained from …
periodontics. Recently mesenchymal stem cells (MSC) have been proposed for tissue
regeneration in periodontal disease and repair of large bone defects. Bone regeneration
has to be supported by a scaffold which has to be biocompatible, biodegradable, and able to
support cell growth and differentiation. The aim of this study was to evaluate osteogenic
differentiation of MSC seeded on a collagen scaffold. DESIGN: MSC were obtained from …
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