Mesenchymal stem cells-derived mitochondria transplantation mitigates I/R-induced injury, abolishes I/R-induced apoptosis, and restores motor function in acute …

Z Pourmohammadi-Bejarpasi, AM Roushandeh… - Brain Research …, 2020 - Elsevier
Acute ischemia stroke (AIS) is one of the leading causes of mortality and disability
worldwide, and its neurological impacts are devastating and permanent. There is no efficient
and real treatment for acute ischemia stroke so far. Therefore, development of efficient
therapeutic strategies is under focus of investigations by basic and clinical scientists. Brain is
one of the organs with high energy consumption and metabolism. Hence, its functionality is
highly dependent on mitochondrial activity and integrity. Therefore, mitochondria play a vital …
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