Mesoporous silica nanoparticles functionalized with folic acid/methionine for active targeted delivery of docetaxel

P Khosravian, M Shafiee Ardestani… - OncoTargets and …, 2016 - Taylor & Francis
Mesoporous silica nanoparticles (MSNs) are known as carriers with high loading capacity
and large functionalizable surface area for target-directed delivery. In this study, a series of
docetaxel-loaded folic acid-or methionine-functionalized mesoporous silica nanoparticles
(DTX/MSN-FA or DTX/MSN-Met) with large pores and amine groups at inner pore surface
properties were prepared. The results showed that the MSNs were successfully synthesized,
having good pay load and pH-sensitive drug release kinetics. The cellular investigation on …

[引用][C] Mesoporous silica nanoparticles functionalized with folic acid/methionine for active targeted delivery of docetaxel. Onco-Targets Ther 9: 7315–7330

P Khosravian, MS Ardestani, M Khoobi, SN Ostad… - 2016
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