For short-term chemical inhalation exposures to hazardous chemicals, the incidence of a
health effect in biological testing usually conforms to a general linear model with a probit link
function dependent on inhalant concentration C and the duration of exposure t. The National
Academy's Acute Exposure Guideline Levels (AEGLs) Committee relies on these models
when establishing AEGLs. Threshold concentrations at AEGL durations are established by
the toxic load equation C nxt= constant, which toxic load exponent n (TLE or n-value) directly …