Meta-hallmarks of aging and cancer

C López-Otín, F Pietrocola, D Roiz-Valle, L Galluzzi… - Cell metabolism, 2023 - cell.com
… Several hallmarks of aging (ie, genomic instability, epigenetic alterations, chronic … cancer
hallmarks and hence constitute common “meta-hallmarks,” while other features of aging (ie, …

Aging and cancer

L Montégut, C López-Otín, G Kroemer - Molecular Cancer, 2024 - Springer
… (ie, genomic instability, epigenetic alterations, chronic inflammation and dysbiosis) are
also described as hallmarks of cancer and hence constitute common ‘meta-hallmarks’ or ‘…

[HTML][HTML] Aging and cancer hallmarks as therapeutic targets

J Wang, JCJ Wei, H Inuzuka - Acta Materia Medica, 2023 - ucl.scienceopen.com
… a complex interplay between aging and cancer. To this end, … aging; therefore, aging is a
significant risk factor for cancer. In 2000 Hanahan and Weinberg [6] originally classified cancer

Clinical biomarker-based biological aging and risk of cancer in the UK Biobank

JKL Mak, CE McMurran, R Kuja-Halkola, P Hall… - … journal of cancer, 2023 - nature.com
aging may lead to increased risks of any cancer, lung cancer, and colorectal cancer, independent
of age, sex, and common cancercancers such as breast cancer and prostate cancer, …

The hallmarks of aging as a conceptual framework for health and longevity research

AG Tartiere, JMP Freije, C López-Otín - Frontiers in Aging, 2024 - frontiersin.org
aging (Abdellatif et al., 2023). Moreover, the Hallmarks have given rise to the concept of
meta-hallmarks of aging and cancer, … In this sense, these meta-hallmarks aimed to illustrate the …

Obesity and risk of diseases associated with hallmarks of cellular ageing: a multicohort study

M Kivimäki, P Frank, J Pentti, X Xu… - The Lancet Healthy …, 2024 - thelancet.com
Background Ageing hallmarks, characterising features of cellular ageing, have a role in the
pathophysiology of many age-related diseases. We examined whether obesity is associated …

Association of Biological Ageing with All-Cause Mortality among Individuals with Tumors: a Cohort Study

Q Bu, C Zhou, Y Yao, DD Duan, S Lu, H Cheng - 2024 - researchsquare.com
… and development of tumors. But the association of biological ageing with tumors remains
elusive. … ageing to all-cause mortality of individuals with tumors and the related risk factors. …

Promoting longevity with less cancer: The 2022 International Conference on Aging and Cancer

Y Cui, K Wang, D Jiang, Y Jiang, D Shi… - … and Cancer, 2023 - Wiley Online Library
aging and cancer and in the development of intervention strategies. However, both aging and
cancerAging or senescence appears to be a consequence of the need to adapt to the ever…

Unravelling the nexus: Towards a unified model of development, ageing, and cancer

A Fontana - Biosystems, 2023 - Elsevier
… , ageing, and cancer. While there have been previous attempts to construct models separately
for two of these phenomena (such as embryogenesis and cancer, ageing and cancer), …

Senotherapy, cancer, and aging

L Balducci, C Falandry, S Monfardini - Journal of Geriatric Oncology, 2023 - Elsevier
… a major achievement in the management of aging, including the treatment of cancer in
older individuals as frail patients, by definition, cannot tolerate aggressive cancer treatment. …