… have conducted preliminary studies on the potential of dried blood spot cards for use in the
storage/sample preparation of whole blood, plasma, and urine in metabolite profiling studies. …

… in 1 H NMR studies [17]. Recently the use of blood spots in metabolic profiling based on …
However, whilst promising, these initial studies did not investigate the long-term stability or …

… coupled with mass-spectrometry-based metabolomics analysis [30] to explore human blood
and urine metabolomic profiling. … of more than 300 polar metabolites in a single DBS/DUS …

… reversed-phase UHPLC-MS untargeted metabolomic assays. Results show that metabolites
… in positive and negative ion modes using a Vanquish UHPLC coupled to an electrospray Q …

… samples yield distinct metabolite profiles highly predictive of … the middle of two spots, then
combined in the extraction plate. … (Waters UPLC BEH Amide 2.1 × 150 mm, 1.7 µm) using a …

… range of metabolites focusing on dried blood spots while still … LC instrumentation used was
a Dionex Ultimate 3000 UHPLC … using an aqueous mix of standards mixed with whole blood (…

… , we employed both positive and negative modes UHPLC-MS … , facilitating robust untargeted
metabolomics studies using … In brief, DBS slices were mixed with 700 µL MTBE buffer …

… in metabolite profiling using UPLC combined with orthogonal acceleration time-of-flight
mass spectrometry (oa-TOF-MS). (5) In this regard, GC/MS has several advantages over UPLC-…

… For this purpose, dried blood spots (DBS) of newborns are a … We used metabolomics profiles
from DBS of newborns (age 2–3 days… A total of three combination were conducted, namely: …

… for global metabolic profiling with, in the case of UPLC–MS-based analysis, the … Metabolite
profiles from dried blood spots for metabonomic studies using UPLC combined with oaToF-…