Background. Metabolic Syndrome (MS) is associated with impaired endothelial function and
increased cardiovascular risk. Insulin resistance is a key feature of MS and plays an
important role in the pathogenesis of endothelial dysfunction. Aim of the present study was
to evaluate the effect of metformin on endothelial function and insulin resistance, assessed
by the homeostasis model (HOMA‐IR, homeostasis model assessment‐insulin resistance),
in patients with MS. Methods. Sixty‐five subjects (37 men and 28 women, mean age 54±6 …

Conclusions: The presence of RF identifies a subgroup of patrents at particularly high risk for
vascular complications and death. This simple marker should prompt evaluation for visceral
and limb ischemia to ensure the use of appropriate medical and surgical strategles lo
reduce morbidity and mortality from AAD. 1034-l 43 Endovascular Stent-Graft Repair of
Descending Thoracic Aortic Penetrating Atherosclerotic Ulcers: Mid-Term Results