… ) expose soft tissues to external thermal devices in an … ) will selectively damage subcutaneous
adipose tissue while leaving the … were added (eg, surface cooling capability) to allow more …

… HIFU approach and multiple passes to induce layered adipose … Zeltiq’s “Coolsculpt” uses
suction coupled “super-cooling” … for a very selective targeting of only the superficial fat and …

… fatty tissue in abdominal and flank areas using a controlled … First device was approved by
the FDA in 2010 (K080521). (4… a non-invasive method of reducing fat tissue. Recent studies …

… in surgical and medical instruments for biological tissue cutting, … With soft tissue loads such
as fat, muscle, liver, skin and … This permitted selective disruption of rigid fibrous elements and …

… fat reduction, surgical lipoplasty remains a popular method for … is initiated when fat cells are
cooled to temperatures between −2 … The focal volume of this nonthermal ultrasound device …

… the selective destruction of adipocytes by cooling is not fully understood. Fat or adipose tissue
… This novel technique has become another noninvasive method of fat removal and body …

… With the Cooltech device, tissue is drawn between parallel anodized aluminum cooling …
increase in fatty tissue develops over the 2–5 months after selective cryolipolysis treatment. …

… of a tissue cryotherapy device aimed at reducing abdominal fat; … Cooling of fatty tissue
has been suggested to lead to adipocyte disruption/cell death and local inflammation (“selective …

… device that was widely incorporated in physicians’ practices was the … It uses nonthermal
selective focused ultrasound to produce … of porcine adipose tissue after treatment with the device …

… With selective cryolysis, precise application of cold … baseline in adipose layer thickness
between device and control based … to extract energy (cooling) from the underlying fat tissue. The …