MiR-SNPs as markers of toxicity and clinical outcome in Hodgkin lymphoma patients
Background In recent years, microRNA (miRNA) pathways have emerged as a crucial
system for the regulation of tumorogenesis. miR-SNPs are a novel class of single nucleotide
polymorphisms that can affect miRNA pathways. Design and Methods We analyzed eight
miR-SNPs by allelic discrimination in 141 patients with Hodgkin lymphoma and correlated
the results with treatment-related toxicity, response, disease-free survival (DFS) and overall
survival (OS). Results The KRT81 (rs3660) GG genotype was associated with an increased …
system for the regulation of tumorogenesis. miR-SNPs are a novel class of single nucleotide
polymorphisms that can affect miRNA pathways. Design and Methods We analyzed eight
miR-SNPs by allelic discrimination in 141 patients with Hodgkin lymphoma and correlated
the results with treatment-related toxicity, response, disease-free survival (DFS) and overall
survival (OS). Results The KRT81 (rs3660) GG genotype was associated with an increased …
MiR-SNPs as markers of toxicity and clinical outcome in Hodgkin Lymphoma patients
A Navarro Ponz, C Muñoz, A Gaya… - … , 2013, vol. 8, num. 5, p …, 2013 - diposit.ub.edu
Background: In recent years, microRNA (miRNA) pathways have emerged as a crucial
system for the regulation of tumorogenesis. miR-SNPs are a novel class of single nucleotide
polymorphisms that can affect miRNA pathways. Design and Methods: We analyzed eight
miR-SNPs by allelic discrimination in 141 patients with Hodgkin lymphoma and correlated
the results with treatment-related toxicity, response, disease-free survival (DFS) and overall
survival (OS). Results: The KRT81 (rs3660) GG genotype was associated with an increased …
system for the regulation of tumorogenesis. miR-SNPs are a novel class of single nucleotide
polymorphisms that can affect miRNA pathways. Design and Methods: We analyzed eight
miR-SNPs by allelic discrimination in 141 patients with Hodgkin lymphoma and correlated
the results with treatment-related toxicity, response, disease-free survival (DFS) and overall
survival (OS). Results: The KRT81 (rs3660) GG genotype was associated with an increased …
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