… We have developed microimaging technologies, implemented novel computational … images
of amyloid deposits in mice. I‐labeled serum amyloid P component (SAP) and an amyloid‐…

… It is likely that the Aβ ligands used in these studies would also label amyloid associated with
cerebral blood vessels. However, the AD-transgenic mice in this study had minimal amyloid …

… While developing these MRI techniques to image individual amyloid plaques in AD
transgenic mice, we have been concurrently developing contrast-enhancing agents that will …

… The visualization of amyloid plaques in the brain is important to monitor AD progression …
amyloid plaques in vivo using magnetic resonance microimaging (μMRI) in AD transgenic mice, …

… amyloid plaques in vivo using magnetic resonance microimaging (µMRI) in AD transgenic
mice… Aβ1-42 peptide to image amyloid plaque deposition in the mouse brain. We coupled the …

… be detected in AD mice as young as 3 … amyloid plaques provides a noninvasive estimate
of plaque burden in transgenic AD mice that might be useful in assessing the efficacy of amyloid …

… by μMRI is clearly significant at 12–18 months of age, we suggest that monitoring the effect
of anti-amyloid drugs in Tg2576 mice during that time window is feasible with in vivo μMRI. …

… As levels of this A subspecies in model mice are lower than those in AD patients, our … mouse
amyloid. Near-simultaneous monitoring of amyloid removal and microgliosis in APP23 mice …

… Although several technical aspects need to be further improved, such as the spatial
resolution of the scanner (∼1.5 mm) (Tai et al., 2005), our results rationalize the use of micro-…

… pipeline that we have reported enables the assessment of the pathology of AD in mouse
models of amyloidosis at multiple scales, from cortex-wide transcranial Aβ mapping with single-…