[HTML][HTML] Micro RNA and its role in the pathophysiology of spinal cord injury—A further step towards neuroregenerative medicine
J Quinzanos-Fresnedo, RC Sahagún-Olmos - Cirugía y Cirujanos (English …, 2015 - Elsevier
Cirugía y Cirujanos (English Edition), 2015•Elsevier
In the pathophysiology of spinal cord injury, the secondary biological processes involving
changes in gene expression become more important day a day. Within these changes, the
expression of different micro RNAs has been involved in some of the pathophysiological
processes of spinal cord injury. There are several studies that describe the transient
expression of micro RNA in spinal cord injury, some of them related to inflammation and
apoptosis and others to functional recovery and regeneration. Micro RNA may be a potential …
changes in gene expression become more important day a day. Within these changes, the
expression of different micro RNAs has been involved in some of the pathophysiological
processes of spinal cord injury. There are several studies that describe the transient
expression of micro RNA in spinal cord injury, some of them related to inflammation and
apoptosis and others to functional recovery and regeneration. Micro RNA may be a potential …
Abstract
In the pathophysiology of spinal cord injury, the secondary biological processes involving changes in gene expression become more important day a day. Within these changes, the expression of different micro RNAs has been involved in some of the pathophysiological processes of spinal cord injury.
There are several studies that describe the transient expression of micro RNA in spinal cord injury, some of them related to inflammation and apoptosis and others to functional recovery and regeneration.
Micro RNA may be a potential target for the treatment of spinal cord injury, modifying the processes of inflammation, oxidation, apoptosis, functional recovery and regeneration.
It is necessary to continue the study of micro RNAs in spinal cord injury, as well as the identification of their target genes and signalling mechanisms involved in its neurological effects. With this, the ultimate goal is the development of effective and safe therapeutic and diagnostic strategies for patients with spinal cord injury.
Elsevier
以上显示的是最相近的搜索结果。 查看全部搜索结果