… targeted microRNA-145–based therapy is associated with a marked reduction in atherosclerotic
… We also report reduced levels of the microRNA-145 target KLF4 in aortas from ApoE −/− …

… A great role in vascular metabolism is played by microRNA-145 (miR-145). MiR-145 is
expressed together with miR-143 in the same bicistronic transcript and is able to promote …

… in atherosclerotic plaques. Given VSMC phenotypic switching is regulated by microRNA-145
(… to VSMCs has the potential to mitigate atherosclerosis development by inhibiting plaque-…

… High-fat diet (HFD)-treated ApoE −/− mice were used as an in vivo model of atherosclerosis
(AS)… targeting of the miR-145/NF−κB pathway may be an effective therapeutic strategy for AS. …

… However, further research focusing on the role of miR-145/CD40 pathway in inflammation
or CVD/atherosclerosis model is still necessary to verify our findings and other pathogenic …

… , microRNA-145, and microRNA-155 has been shown to be associated with atherosclerotic
lesion … The aim of this study was to evaluate the association between atherosclerosis-related …

… VSMC-targeted, atherosclerosis therapies. Previously, we reported on the efficacy of
microRNA-145 (miR-145) as a therapy for atherosclerosis when delivered as part of a targeted, …

… to nearly undetectable levels in atherosclerotic arteries, an even more pronounced change
… If the selected atherosclerotic tissue had fewer VSMCs, the expression level of miR-145 …

… However, miR-126 overexpression can reduce atherosclerosis, indicating an alternative
target of miR-126 considering the proatherogenic role of vascular endothelial growth factor. …

… Mesenchymal stem cells (MSCs) exhibit therapeutic effects for the treatment of … atherosclerosis.
In this study, we show that microRNA-145 (miR-145) is associated with atherosclerosis …