Micronucleus Score in the Buccal Mucosa of Women with Breast Cancer and the Relationship to Chemotherapy
ME Kalender, IH Yildirim, M Ulasli… - Annals of …, 2014 - annalsofoncology.org
Background: There are multiple genomic differences between healthy women and women
with breast cancer. Chromosomal damage and loss can be detected through cytogenetic
methods, one of which is the micronucleus (MN) assay. This study is designed to evaluate
the genomic differences between healthy women and women with breast cancer through the
MN assay. Methods: This study included 32 healthy women and 24 breast cancer patients.
The buccal smears of breast cancer patients were taken three times: before chemotherapy …
with breast cancer. Chromosomal damage and loss can be detected through cytogenetic
methods, one of which is the micronucleus (MN) assay. This study is designed to evaluate
the genomic differences between healthy women and women with breast cancer through the
MN assay. Methods: This study included 32 healthy women and 24 breast cancer patients.
The buccal smears of breast cancer patients were taken three times: before chemotherapy …
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