[PDF][PDF] Microsystem for biological analysis based on magnetoresistive sensing

J Germano, MS Piedade, L Sousa… - XVIII International …, 2006 - academia.edu
XVIII International Measurement Confederation (IMEKO) World Congress, 2006academia.edu
This paper presents a microsystem for biomolecular recognition (DNA, enzymes) based on a
biochip, which uses magnetic field arraying of magnetically tagged biomolecules and high
sensitivity sensors for single biomolecule detection. The microsystem provides the electronic
circuitry for addressing, reading out and sensing each of the 16× 16 magnetoresistive
sensors that compose the biochip. A prototype of the microsystem was developed and
experimental results show that it is able of nanoparticle detection and, consequently, be …
Abstract
This paper presents a microsystem for biomolecular recognition (DNA, enzymes) based on a biochip, which uses magnetic field arraying of magnetically tagged biomolecules and high sensitivity sensors for single biomolecule detection. The microsystem provides the electronic circuitry for addressing, reading out and sensing each of the 16× 16 magnetoresistive sensors that compose the biochip. A prototype of the microsystem was developed and experimental results show that it is able of nanoparticle detection and, consequently, be used for magnetic labelled based bioassays.
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