… viral regulation. Would non-canonical necrosomes such as ZBP1-RIPK3 be hybrid amyloids
akin to the canonical RIPK1-RIPK3 necrosome? Could viral RHIM … , via the viral RHIM. Not …

… defense, a few DNA viruses (herpesviruses) have evolved to mimic host RHIMs to counteract
… Also, our observations indicate bat RHIM-proteins in driving the evolution of viral RHIMs in …

… We have identified a novel viral RHIM in the VZV capsid triplex protein, open reading frame
(… the viral RHIM in M45 from murine cytomegalovirus that inhibits cell death, the ORF20 RHIM …

… of these infections poses a major challenge in immunocompromised patients [55,56],
overcoming pathogen persistence would be a substantial therapeutic advantage: the viral RHIM …

… Our results indicate that M45 mimics the interactions made by … The affinity of the viral RHIM
is similar for RIPK3 and ZBP1. … the viral M45 RHIM alters the properties of the human RHIM-…

… We focus on the modulation of assembly formation by assembly component mimics or decoys
… mechanisms regulating SCAF in the corresponding pathways through molecular mimics. …

… Although viral mimics override host regulation, cellular FLIP in the Casp8–FADD–FLIP … ,
murine CMV deploys viral inhibitor of RIP activation (vIRA) as a potent RHIM-dependent inhibitor …

… viral RHIM inhibitors are absent, ZBP1 senses viral RNA (vRNA) to trigger RIPK3 binding and
activation. The necroptosis modulating function of these viral RHIM … I:C), which mimics viral …

… We show that viral MLKL-like proteins function as dominant-negative mimics of host MLKL,
which … Most viral effectors reported to block necroptosis target the RHIM sequences of RIPK1, …

… and mimic normal … viral immortalizing genes. We have established a prostatic epithelial
cell line PWR-1E, immortalized by an adenovirus 12-Simian virus 40 (Adl2-SV40) hybrid virus. …