Mitochondrial pathway is involved in advanced glycation end products-induced apoptosis of rabbit annulus fibrosus cells
Y Hu, Z Shao, X Cai, Y Liu, M Shen, Y Yao, T Yuan… - Spine, 2019 - journals.lww.com
Study Design. Experimental study. Objective. The purposes of this study were to evaluate
whether advanced glycation end-products (AGEs) induce annulus fibrosus (AF) cell
apoptosis and further to explore the mechanism by which this process occurs. Summary of
Background Data. Recent studies revealed that AGEs accumulation is considered an
important factor in diabetic intervertebral disc (IVD) degeneration. However, the effect of
AGEs on intervertebral disc remains unclear. Methods. AF cells were treated with various …
whether advanced glycation end-products (AGEs) induce annulus fibrosus (AF) cell
apoptosis and further to explore the mechanism by which this process occurs. Summary of
Background Data. Recent studies revealed that AGEs accumulation is considered an
important factor in diabetic intervertebral disc (IVD) degeneration. However, the effect of
AGEs on intervertebral disc remains unclear. Methods. AF cells were treated with various …
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