Modelling late stool frequency and rectal pain after radical radiotherapy in prostate cancer patients: Results from a large pooled population
A Cicchetti, T Rancati, M Ebert, C Fiorino, F Palorini… - Physica Medica, 2016 - Elsevier
Aim To investigate late gastrointestinal toxicity in a large pooled population of prostate
cancer patients treated with radical radiotherapy. Normal tissue complication probability
models were developed for late stool frequency and late rectal pain. Methods and materials
Population included 1336 patients, 3-year minimum follow-up, treated with 66–80 Gy.
Toxicity was scored with LENT-SOMA-scale. Two toxicity endpoints were considered:
grade⩾ 2 rectal pain and mean grade (average score during follow-up) in stool frequency> …
cancer patients treated with radical radiotherapy. Normal tissue complication probability
models were developed for late stool frequency and late rectal pain. Methods and materials
Population included 1336 patients, 3-year minimum follow-up, treated with 66–80 Gy.
Toxicity was scored with LENT-SOMA-scale. Two toxicity endpoints were considered:
grade⩾ 2 rectal pain and mean grade (average score during follow-up) in stool frequency> …
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