Modulating phenylalanine metabolism by L. acidophilus alleviates alcohol-related liver disease through enhancing intestinal barrier function

L Chen, P Yang, L Hu, L Yang, H Chu, X Hou - Cell & Bioscience, 2023 - Springer
Background Impaired metabolic functions of gut microbiota have been demonstrated in
alcohol-related liver disease (ALD), but little is known about changes in phenylalanine
metabolism. Methods Bacterial genomics and fecal metabolomics analysis were used to
recognize the changes of phenylalanine metabolism and its relationship with intestinal flora.
Intestinal barrier function was detected by intestinal alkaline phosphatase (IAP) activity,
levels of tight junction protein expression, colonic inflammation and levels of serum LPS …

Modulating phenylalanine metabolism by L. acidophilus alleviates alcohol-related liver disease through enhancing intestinal barrier function

C Liuying, Y Pengcheng, H Lilin, Y Ling… - Cell & Bioscience …, 2023 - jglobal.jst.go.jp
acidophilus alleviates alcohol-related liver disease through enhancing intestinal barrier
function | Article Information | J-GLOBAL … Alcohol-related liver diseases About Alcohol-related
liver diseases
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