[HTML][HTML] Modulation of apoptosis in HaCaT keratinocytes via differential regulation of ERK signaling pathway by flavonoids
The exact molecular mechanisms underlying the cellular effects associated with various
flavonoids have yet to be fully explained. In the present study, we have administered several
flavonoids to human HaCaT keratinocytes and determined that 3, 4′-dihydroxy flavone (3,
4′-DHF) exerts a slight stimulatory effect on cell growth, although other flavonoids,
including kaempferol, quercetin, and isorhamnetin, exhibited growth inhibitory properties. 3,
4′-DHF was found to exert an anti-apoptotic effect on etoposide-induced cell death of …
flavonoids have yet to be fully explained. In the present study, we have administered several
flavonoids to human HaCaT keratinocytes and determined that 3, 4′-dihydroxy flavone (3,
4′-DHF) exerts a slight stimulatory effect on cell growth, although other flavonoids,
including kaempferol, quercetin, and isorhamnetin, exhibited growth inhibitory properties. 3,
4′-DHF was found to exert an anti-apoptotic effect on etoposide-induced cell death of …
Modulation of apoptosis in HaCaT keratinocytes via differential regulation of ERK signaling pathway by flavonoids.
LER Lee EungRyoung, KYJ Kang YongJin… - 2005 - cabidigitallibrary.org
The exact molecular mechanisms underlying the cellular effects associated with various
flavonoids have yet to be fully explained. In the present study, we have administered several
flavonoids to human HaCaT keratinocytes and determined that 3, 4′-dihydroxy flavone (3,
4′-DHF) exerts a slight stimulatory effect on cell growth, although other flavonoids,
including kaempferol, quercetin, and isorhamnetin, exhibited growth inhibitory properties. 3,
4′-DHF was found to exert an anti-apoptotic effect on etoposide-induced cell death of …
flavonoids have yet to be fully explained. In the present study, we have administered several
flavonoids to human HaCaT keratinocytes and determined that 3, 4′-dihydroxy flavone (3,
4′-DHF) exerts a slight stimulatory effect on cell growth, although other flavonoids,
including kaempferol, quercetin, and isorhamnetin, exhibited growth inhibitory properties. 3,
4′-DHF was found to exert an anti-apoptotic effect on etoposide-induced cell death of …
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