The mesencephalic locomotor region (MLR) serves as an interface between higher-order
motor systems and lower motor neurons. The excitatory module of the MLR is composed of
the pedunculopontine nucleus (PPN) and the cuneiform nucleus (CnF), and their activation
has been proposed to elicit different modalities of movement. However, how the differences
in connectivity and physiological properties explain their contributions to motor activity is not
well known. Here we report that CnF glutamatergic neurons are more electrophysiologically …