Modulatory effects of inhibition on persistent activity in a cortical microcircuit model
Neocortical network activity is generated through a dynamic balance between excitation,
provided by pyramidal neurons, and inhibition, provided by interneurons. Imbalance of the
excitation/inhibition ratio has been identified in several neuropsychiatric diseases, such as
schizophrenia, autism and epilepsy, which also present with other cognitive deficits and
symptoms associated with prefrontal cortical (PFC) dysfunction. We undertook a
computational approach to study how changes in the excitation/inhibition balance in a PFC …
provided by pyramidal neurons, and inhibition, provided by interneurons. Imbalance of the
excitation/inhibition ratio has been identified in several neuropsychiatric diseases, such as
schizophrenia, autism and epilepsy, which also present with other cognitive deficits and
symptoms associated with prefrontal cortical (PFC) dysfunction. We undertook a
computational approach to study how changes in the excitation/inhibition balance in a PFC …
Modulatory effects of inhibition on persistent activity in a cortical microcircuit model
X Konstantoudaki, A Papoutsi… - … and Modeling of …, 2016 - books.google.com
Neocortical network activity is generated through a dynamic balance between excitation,
provided by pyramidal neurons, and inhibition, provided by interneurons. Imbalance of the
excitation/inhibition ratio has been identified in several neuropsychiatric diseases, such as
schizophrenia, autism and epilepsy, which also present with other cognitive deficits and
symptoms associated with prefrontal cortical (PFC) dysfunction. We undertook a
computational approach to study how changes in the excitation/inhibition balance in a PFC …
provided by pyramidal neurons, and inhibition, provided by interneurons. Imbalance of the
excitation/inhibition ratio has been identified in several neuropsychiatric diseases, such as
schizophrenia, autism and epilepsy, which also present with other cognitive deficits and
symptoms associated with prefrontal cortical (PFC) dysfunction. We undertook a
computational approach to study how changes in the excitation/inhibition balance in a PFC …
以上显示的是最相近的搜索结果。 查看全部搜索结果