In a series of 45 poorly differentiated adenocarcinomas (por) and 7 signet‐ring‐cell
carcinomas (sig) of the colorectum, K‐ras gene mutation, p53 immunostaining and
microsatellite instability (MSI) were analyzed for a comparison with 46 cases of colorectal
carcinomas of the well or moderately differentiated type (well/mod). In addition, the
mutations of simple repeated sequences in the transforming‐growth‐factor‐β type‐II
receptor (T β R‐II) gene and the BAX gene were analyzed as possible targets for DNA …

… Title MOLECULAR CHARACTERISTICS OF POORLY DIFFERENTIATED
ADENOCARCINOMA AND SIGNET RING CELL CARCINOMA OF COLORECTUM …