Molecular characterization and comparison of four Anisakis allergens between Anisakis simplex sensu stricto and Anisakis pegreffii from Japan

KMA Quiazon, K Zenke, T Yoshinaga - Molecular and biochemical …, 2013 - Elsevier
It remains unclear whether allergens are the same among the sibling species of Anisakis
simplex sensu lato. This study was carried out to compare the amino acid sequences of
three major (Ani s 1, 2 and 12) and one minor (Ani s 9) Anisakis allergens between A.
simplex ss and Anisakis pegreffii. We found 2 (out of 163), 1 (out of 869), and 29 (out of 266)
amino acid variable sites for Ani s 1, 2, and 12, respectively. However, as both intra-and inter-
species variations were present at the same amino acid positions, no amino acid variations …
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