Molecular characterization of P-29, a metacestode-specific component of Echinococcus granulosus which is immunologically related to, but distinct from, antigen 5
G González, P Spinelli, C Lorenzo, U Hellman… - Molecular and …, 2000 - Elsevier
In this work the characterization of P-29, a novel 29 kDa antigen from Echinococcus
granulosus is reported. E. granulosus was identified while looking for parasite antigens
distinct from those present in hydatid cyst fluid. A monoclonal antibody (mAb 47H. PS)
prepared against protoscolex components revealed that P-29 is localized to the tegument
and rostellum of protoscoleces, and to the germinal layer of the cyst, but it is absent in
hydatid cyst fluid or adult worm extracts. Several internal fragments of P-29 showed …
granulosus is reported. E. granulosus was identified while looking for parasite antigens
distinct from those present in hydatid cyst fluid. A monoclonal antibody (mAb 47H. PS)
prepared against protoscolex components revealed that P-29 is localized to the tegument
and rostellum of protoscoleces, and to the germinal layer of the cyst, but it is absent in
hydatid cyst fluid or adult worm extracts. Several internal fragments of P-29 showed …
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