Molecules, maps and synapse specificity

DL Benson, DR Colman, GW Huntley - Nature Reviews Neuroscience, 2001 - nature.com
… how synapse specificity is achieved, many of them proposed before the identification of
guidance or recognition molecules… the molecular underpinnings of axon guidance, targeting and …

Synaptic specificity, recognition molecules, and assembly of neural circuits

JR Sanes, SL Zipursky - Cell, 2020 - cell.com
… combinatorial use of multifunctional recognition molecules underlie synaptic specificity. …
A cellular definition of synaptic specificity is required for understanding the molecular

Many paths to synaptic specificity

JR Sanes, M Yamagata - Annual Review of Cell and …, 2009 - annualreviews.org
… uncommon for molecules involved in synapse formation to … laminar specificity is a major
contributor to synaptic specificity … of a crude map by an activity-independent molecular matching …

Molecular mechanisms of synaptic specificity

MA Margeta, K Shen - Molecular and Cellular Neuroscience, 2010 - Elsevier
… neuronal wiring, and suggested that orderly mapping that utilized multiple molecular gradients
could lead to the development of topographic maps (Sperry, 1963). Subsequent work has …

Molecular mechanisms of synaptic specificity in developing neural circuits

ME Williams, J de Wit, A Ghosh - Neuron, 2010 - cell.com
… precision of synaptic connections that … of synapses at particular regions on postsynaptic
neurons. Much of our understanding of the molecular basis of synaptic specificity and synaptic

Cortical plasticity: from synapses to maps

DV Buonomano, MM Merzenich - Annual review of …, 1998 - annualreviews.org
… Investigators have made manyimportant strides toward understanding the molecular
pathway specificity. It has been suggested that thespines on which Ex → Ex synapses generally …

Molecular heterogeneity of central synapses: afferent and target regulation

AM Craig, H Boudin - Nature neuroscience, 2001 - nature.com
… Indeed, we believe that each individual synapse is unique, a function of presynaptic cell
type… We review here the molecular diversity of glutamatergic and GABAergic synapses in the …

Deep molecular diversity of mammalian synapses: why it matters and how to measure it

NA O'rourke, NC Weiler, KD Micheva… - Nature Reviews …, 2012 - nature.com
… The lower panels show how this method can be used to map synaptic proteins onto a
common trans-synaptic coordinate system defined by Homer 1 for the postsynaptic side and …

The cell biology of synaptic specificity during development

R Christensen, Z Shao, DA Colon-Ramos - Current Opinion in …, 2013 - Elsevier
… In this review, we focus discussion on recently elucidated molecular mechanisms that
control synaptic specificity and link them to … Molecules, maps and synapse specificity

Molecular mechanisms of presynaptic differentiation

Y Jin, CC Garner - Annual review of cell and developmental …, 2008 - annualreviews.org
… the specificity and dynamics of synapses. This review highlights the recent findings pertaining
to the cellular and molecular … of the MAP-1B protein Futsch causes a reduction of synaptic