[HTML][HTML] Molnupiravir—a novel oral anti-SARS-CoV-2 agent

CC Lee, CC Hsieh, WC Ko - Antibiotics, 2021 - mdpi.com
… report is to provide a detailed overview of molnupiravir, an oral and novel RdRp inhibitor. …
In summary, these studies indicate that oral molnupiravir is highly effective in reducing …

A systematic review of the global intervention for SARS-CoV-2 combating: from drugs repurposing to molnupiravir approval

NA Ashour, A Abo Elmaaty, AA Sarhan… - Drug design …, 2023 - Taylor & Francis
… available oral anti-SARS-CoV-2 candidates, as a new hope to end the current pandemic. …
, on the other hand, assessed inhaled ribavirin preparation as a sole agent. Citation100 …

The preclinical discovery and development of molnupiravir for the treatment of SARS-CoV-2 (COVID-19)

P Pagliano, C Sellitto, T Ascione… - Expert Opinion on …, 2022 - Taylor & Francis
Molnupiravir (MOV) is a broad-spectrum oral antiviral agentMolnupiravir for oral
treatment of covid-19 in nonhospitalized … and safety of three new oral antiviral treatment (molnupiravir, …

[HTML][HTML] Molnupiravir and its antiviral activity against COVID-19

L Tian, Z Pang, M Li, F Lou, X An, S Zhu… - Frontiers in …, 2022 - frontiersin.org
… or other antiviral biological agents such as convalescent … developed a new strategy to
synthesize molnupiravir using … partly explain why the anti-SARS-CoV-2 activity of remdesivir in …

[HTML][HTML] Interactions of the Anti-SARS-CoV-2 Agents Molnupiravir and Nirmatrelvir/Paxlovid with Human Drug Transporters

É Bakos, C Temesszentandrási-Ambrus… - International Journal of …, 2023 - mdpi.com
… drug–transporter interactions of Molnupiravir, Nirmatrelvir, and … In the case of the nucleoside
analog Molnupiravir, we included … side effects of these widely used anti-COVID-19 agents. …

Comprehensive review on molnupiravir in COVID-19: a novel promising antiviral to combat the pandemic

S Khiali, E Khani, SB Rouy… - Future Microbiology, 2022 - Taylor & Francis
oral antiviral agents are still lacking. In the present review, the potential beneficial effects of
molnupiravir in … be considered as disadvantages of anti-SARS-CoV-2 monoclonal antibodies. …

[HTML][HTML] Antiviral activity of molnupiravir against COVID-19: a schematic review of evidences

S Singla, S Goyal - Bulletin of the National Research Centre, 2022 - Springer
Anti-SARS-CoV-2 treatment for patients with a suspected or confirmed COVID-19 infection …
In this study, NHC was described as a potent anti-VEEV agent, with an EC50 below 1 μM and …

[HTML][HTML] Molnupiravir: A versatile prodrug against SARS-CoV-2 variants

D Teli, P Balar, K Patel, A Sharma, V Chavda, L Vora - Metabolites, 2023 - mdpi.com
… It is rapidly converted into its active form after oral … on molnupiravir, a nucleoside prodrug,
and its active metabolites, which exhibit promise as broad-spectrum anti-SARS-CoV-2 agents

[HTML][HTML] Review on molnupiravir as a promising oral drug for the treatment of COVID-19

E Zarenezhad, M Marzi - Medicinal Chemistry Research, 2022 - Springer
… Merck and Ridgeback Bio collaborate to develop of a newnew synthetic pathway of
molnupiravir as an anti-viral agent to … -2, molnupiravir has shown strong anti-SARS-CoV-2 activity …

[HTML][HTML] First-generation oral antivirals against SARS-CoV-2

P Sendi, RR Razonable, SB Nelson, A Soriano… - Clinical Microbiology …, 2022 - Elsevier
molnupiravir), and compliance with ingestion of a high number of pills. Knowledge gaps include
the efficacy of these agents … , anti-SARS-CoV-2 monoclonal antibody plus oral antivirals) …