The use of monoliths, one‐piece porous separation materials, as column packaging media
is known as monolithic chromatography and this technology has been widely exploited to
improve the separation profile of high‐valued biomolecules from complex biological
matrices. Monoliths possess a wide range of processing advantages over commonly used
chromatographical resins, including: fast flow rates, short processing times, sufficient surface
area interactions, and enhanced thoroughness. The application of three different types of …