Morphogenesis of Streptomyces in submerged cultures

D van Dissel, D Claessen, GP van Wezel - Advances in applied …, 2014 - Elsevier
Members of the genus Streptomyces are mycelial bacteria that undergo a complex
multicellular life cycle and propagate via sporulation. Streptomycetes are important industrial
microorganisms, as they produce a plethora of medically relevant natural products, including
the majority of clinically important antibiotics, as well as a wide range of enzymes with
industrial application. While development of Streptomyces in surface-grown cultures is well
studied, relatively little is known of the parameters that determine morphogenesis in …
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