The aim of this paper is to provide a summary of structural or surface modifications of vertebrate bone remains in continental palaeoenvironments that may have repercussions on their chemical composition. Both before and after burial, a different set of physical, chemical and biological agencies may produce modifications of the bone morphological structure and/or bone chemical composition. Several of these morphological modifications are diagnostic of particular agents, which otherwise may not be noticed or identified in a fossil association. In order to understand diagenesis, those events that occurred before final burial have to be considered, as they may strongly modify the bone morphological structure and influence post–burial changes.